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Symbol
Name
ID
Myc
myelocytomatosis oncogene
MGI:97250
Phenotype annotations related to liver/biliary system
*Aspects of the system are reported to show a normal phenotype.
Darker colors indicate more annotations
Human Phenotypes
Abnormality of the liver
Disease(s) Associated with MYC
Burkitt lymphoma

Mouse Phenotypes
liver/biliary system phenotype
abnormal liver sinusoid morphology
liver vascular congestion
abnormal hepatocyte mitochondrial morphology
focal hepatic necrosis
enlarged liver
increased liver weight
decreased liver glycogen level
increased liver iron level
abnormal liver morphology
abnormal liver lobule morphology
abnormal hepatocyte morphology
small liver
liver hypoplasia
microvesicular hepatic steatosis
increased hepatocellular carcinoma incidence
increased hepatoma incidence
increased liver adenoma incidence
jaundice
Availability Mouse Genotype
Tg(HBVX*,-Myc)#Skp/Tg(HBVX*,-Myc)#Skp
Tg(Alb1-Myc)#Sst/0
Tg(Ela1-Myc)158Bri/0
Tg(Ela1-Myc)159Bri/0
Tg(Ela1-Myc)160Bri/0
Tg(HBVX*,-Myc)#Skp/0
Tg(Pklr-Myc)73Ak/0
Myctm2.1Atp/Myctm2.1Atp
Edil3Tg(Sox2-cre)1Amc/Edil3+  (conditional)
Myctm2.1Atp/Myctm2.1Atp
Tg(Tek-cre)1Rwng/0  (conditional)
Hnf4atm1(cre)Sdv/Hnf4a+
Myctm2.1Atp/Myctm2.1Atp  (conditional)
*

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory